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Eric Walser's avatar

Sure thing.

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Howard Wolinsky's avatar

Thanks for your comments, Dr. Walser. I appreciated your terminology with "focal therapists" and "magnetic surveillance." Do you think there should be an age cut-off on AS--say at age 75--depending on history and overall health? HW

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Eric Walser's avatar

I think we should stop AS and PSA testing at 80. Many 75 year olds today are pretty healthy and vibrant and have many years to enjoy!

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Howard Wolinsky's avatar

Dr. W. Could you contact me at

howard.wolinsky@gmail.com

I have some questions

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Eric Walser's avatar

As a provider who sees many many of these patients, I agree with the comment that several practitioners are riding the fear of low risk prostate cancer and promoting expensive focal therapies which result in the same long-term cure as doing nothing. Unfortunately, many such prostate "centers" cannot take medicare payments for anything--including MRI exams, ultrasounds, PSA testing, etc since these physicians have largely "opted out" of CMS plans. A prostate "Focal" therapist should have the billing support to authorize payments for these procedures (as possible), should maintain a database and follow their recurrence and complication rates, and should limit focal treatments to significant lesions after consultation with the patient and his partner.

I agree that most Gleason 6 cancers should be left alone and we monitor most of these patients who have such lesions with "magnetic surveillance" which is periodic PSA checks and yearly to every-other yearly MRI exams. Most of these lesions found by blind biopsy are MRI-invisible and we monitor them to make sure they stay that way in the face of stable PSA values.

One caveat here is that Gleason 6 biopsies obtained from "blind" office biopsy will miss lesions in front of the prostate or way back towards the base. I have many patients with high PSA levels who have a blind biopsy for gleason 6 but have an obvious cancer by MRI which we target biopsy and discover Gleason 7 or higher. Active surveillance or magnetic surveillance for prostate cancer requires MRI imaging to rule out these lesions missed with non-targeted biopsy. I have seen several patients with rising PSA levels and 6 or 7 years of annual negative or low-risk biopsies who have an obvious prostate cancer on MRI located in those difficult locations.

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